Happy Birthday, Enovid-10! Friday, 09 May 2008 07:24:45 CDT David-Braverman General, Politics (0) On this day in 1960, the FDA approved Enovid-10, the first commercially-produced oral contraceptive, for general use. The pill, produced by Searle, was yet another earth-shakingly-cool thing to come out of Chicago in the last 50 years.